Responseto Shuchi Parikh`s Initial Post
The post is quite informative and covers all the required questions.However, the post should have provided more information on the birthcontrols pill history, late birth, and breastfeeding history too.First, Phipps et al, (2011) insists thatmost women, who get their first child while they are 35 years andover are more likely to get breast cancer. In this case, JM got herfirst child when she was 34 years, and that shows that she is likelyto be affected by breast cancer. During childbirth, the breast cellsoften multiply rapidly hence, if the breast has genetic damage, thechances of the damage being copied is higher (Lodha et al., 2011). Infact, the older women tend to have higher chances of genetic damagein their cells proving that the late childbirth is highly risky. Thepresence of the hormones estrogen and progestogen in the birthcontrol pills has been associated with the development of cancer(Plu-Bureau, Maitrot-Mantelet, Hugon- Rodin, & Canonico, 2013).The high estrogen often leads to the growth of the cancerous cells.Hence, the 7-8 history of birth control history might facilitate thespread of the cancerous cells. Kotsopoulos et al, (2012) reveals thatbreastfeeding often reduces the risk of a mother getting breastcancer. However, JM will not have the protective benefit since shehas never breastfed in her life. The factors are quite important indetermining the way that JM will be free from the risk of havingbreast cancer. More importantly, the post has listed a number ofconcepts that are quite important in determining if JM has breastcancer or not. All in all, assessing the issues concerned will help amedical practitioner in determining the particular problem and theparticular treatment approach that will reduce the cancer.
Kotsopoulos, J., Lubinski, J., Salmena, L., Lynch, H. T., Kim-Sing,C., Foulkes, W. D., … & Ainsworth, P. (2012). Breastfeeding andthe risk of breast cancer in BRCA1 and BRCA2 mutation carriers.Breast Cancer Research, 14(2), 1.
Lodha, R. S., Nandeshwar, S., Pal, D. K., Shrivastav, A., Lodha, K.M., Bhagat, V. K., … & Saxena, D. M. (2011). Risk factors forbreast cancer among women in Bhopal urban agglomerate: a case-controlstudy. Asian Pac J Cancer Prev, 12(8), 2111-5.
Phipps, A. I., Chlebowski, R. T., Prentice, R., McTiernan, A.,Wactawski-Wende, J., Kuller, L. H., … & Kabat, G. C. (2011).Reproductive history and oral contraceptive use in relation to riskof triple-negative breast cancer. Journal of the National CancerInstitute, 103(6), 470-477.
Plu-Bureau, G., Maitrot-Mantelet, L., Hugon-Rodin, J., &Canonico, M. (2013). Hormonal contraceptives and venousthromboembolism: an epidemiological update. Best Practice &Research Clinical Endocrinology & Metabolism, 27(1),25-34.